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Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

After integration in the host cell genome, the HIV-1 provirus is packaged into chromatin. A specific chromatin disruption occurs in the HIV-1 promoter during transcriptional activation in response to TNF-alpha, suggesting that chromatin plays a repressive role in HIV-1 transcription and that chromat...

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Autors principals: Van Lint, C, Emiliani, S, Ott, M, Verdin, E
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC450009/
https://ncbi.nlm.nih.gov/pubmed/8605881
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