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Axonal Terminals Exposed to Amyloid-β May Not Lead to Pre-Synaptic Axonal Damage

BACKGROUND: Synaptic deficits and neuronal loss are the major pathological manifestations of Alzheimer’s disease. However, the link between the early synaptic loss and subsequent neurodegeneration is not entirely clear. Cell culture studies have shown that amyloid-β (Aβ) applied to axonal terminals...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Alzheimers Dis
Egile Nagusiak: Sun, Shu-Wei, Nishioka, Christopher, Labib, Wessam, Liang, Hsiao-Fang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500050/
https://ncbi.nlm.nih.gov/pubmed/25697704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-142154
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