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DNA repair domains within a human gene: selective repair of sequences near the transcription initiation site.

We describe a new form of DNA repair heterogeneity along the genome. The repair rate of UV-induced cyclobutane pyrimidine dimers (CPDs) was measured at single nucleotide resolution along the promoter and transcribed sequences of the human JUN gene in UV-irradiated diploid fibroblasts. The promoter o...

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Détails bibliographiques
Auteurs principaux: Tu, Y, Tornaletti, S, Pfeifer, G P
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC449986/
https://ncbi.nlm.nih.gov/pubmed/8599951
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