Therapeutic intracoronary gene delivery of VEGF-B(167) in a preclinical animal model of dilated cardiomyopathy

BACKGROUND: Vascular endothelial growth factor-B (VEGF-B) activates cytoprotective/antiapoptotic and minimally angiogenic mechanisms via VEGF receptors. Therefore, VEGF-B might prove an ideal candidate for the treatment of dilated cardiomyopathy, which displays modest microvascular rarefaction and i...

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Bibliografiske detaljer
Udgivet i:J Am Coll Cardiol
Main Authors: Woitek, Felix, Zentilin, Lorena, Hoffman, Nicholas E., Powers, Jeffrey, Ottiger, Isabel, Parikh, Suraj, Kulczycki, Anna M., Hurst, Marykathryn, Ring, Nadja, Wang, Tao, Shaikh, Farah, Gross, Polina, Singh, Harinder, Kolpakov, Mikhail A., Linke, Axel, Houser, Steven R., Rizzo, Victor, Sabri, Abdelkarim, Madesh, Muniswamy, Giacca, Mauro, Recchia, Fabio A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499859/
https://ncbi.nlm.nih.gov/pubmed/26160630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2015.04.071
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