Rapid intraoperative visualization of breast lesions with γ-glutamyl hydroxymethyl rhodamine green

We previously developed γ-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) as a tool to detect viable cancer cells, based on the fact that the enzyme γ-glutamyltranspeptidase (GGT) is overexpressed on membranes of various cancer cells, but is not expressed in normal tissue. Cleavage of the probe b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ueo, Hiroki, Shinden, Yoshiaki, Tobo, Taro, Gamachi, Ayako, Udo, Mitsuaki, Komatsu, Hisateru, Nambara, Sho, Saito, Tomoko, Ueda, Masami, Hirata, Hidenari, Sakimura, Shotaro, Takano, Yuki, Uchi, Ryutaro, Kurashige, Junji, Akiyoshi, Sayuri, Iguchi, Tomohiro, Eguchi, Hidetoshi, Sugimachi, Keishi, Kubota, Yoko, Kai, Yuichiro, Shibuta, Kenji, Kijima, Yuko, Yoshinaka, Heiji, Natsugoe, Shoji, Mori, Masaki, Maehara, Yoshihiko, Sakabe, Masayo, Kamiya, Mako, Kakareka, John W., Pohida, Thomas J., Choyke, Peter L., Kobayashi, Hisataka, Ueo, Hiroaki, Urano, Yasuteru, Mimori, Koshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499838/
https://ncbi.nlm.nih.gov/pubmed/26165706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12080
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