Glutamatergic Effects of Divalproex in Manic Adolescents: A Proton Magnetic Resonance Spectroscopy Study

OBJECTIVES: This study used proton magnetic resonance spectroscopy ((1)H MRS) to evaluate the in vivo effects of extended-release divalproex sodium on the glutamatergic system in adolescents with bipolar disorder and to identify baseline neurochemical predictors of clinical remission. METHOD: Adoles...

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Pubblicato in:J Am Acad Child Adolesc Psychiatry
Autori principali: Strawn, Jeffrey R., Patel, Nick C., Chu, Wen-Jang, Lee, Jing-Huei, Adler, Caleb M., Kim, Mi Jung, Bryan, Holly S., Alfieri, David C., Welge, Jeffrey A., Blom, Thomas J., Nandagopal, Jayasree J., Strakowski, Stephen M., DelBello, Melissa P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499458/
https://ncbi.nlm.nih.gov/pubmed/22632623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaac.2012.03.009
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