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Conjugation of toll-like receptor-7 agonist to gastric cancer antigen MG7-Ag exerts antitumor effects

AIM: To investigate the effects of our tumor vaccines on reversing immune tolerance and generating therapeutic response. METHODS: Vaccines were synthesized by solid phase using an Fmoc strategy, where a small molecule toll-like receptor-7 agonist (T7) was conjugated to a monoclonal gastric cancer 7...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:World J Gastroenterol
Prif Awduron: Wang, Xiao-Dong, Gao, Ning-Ning, Diao, Yu-Wen, Liu, Yu, Gao, Dong, Li, Wang, Wan, Yan-Yan, Zhong, Jing-Jing, Jin, Guang-Yi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Baishideng Publishing Group Inc 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499347/
https://ncbi.nlm.nih.gov/pubmed/26185376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i26.8052
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