A Protein-Based Pentavalent Inhibitor of the Cholera Toxin B-Subunit**

Protein toxins produced by bacteria are the cause of many life-threatening diarrheal diseases. Many of these toxins, including cholera toxin (CT), enter the cell by first binding to glycolipids in the cell membrane. Inhibiting these multivalent protein/carbohydrate interactions would prevent the tox...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Branson, Thomas R, McAllister, Tom E, Garcia-Hartjes, Jaime, Fascione, Martin A, Ross, James F, Warriner, Stuart L, Wennekes, Tom, Zuilhof, Han, Turnbull, W Bruce
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2014
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499251/
https://ncbi.nlm.nih.gov/pubmed/24989497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404397
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