Global transcription network incorporating distal regulator binding reveals selective cooperation of cancer drivers and risk genes

Global network modeling of distal regulatory interactions is essential in understanding the overall architecture of gene expression programs. Here, we developed a Bayesian probabilistic model and computational method for global causal network construction with breast cancer as a model. Whereas physi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kim, Kwoneel, Yang, Woojin, Lee, Kang Seon, Bang, Hyoeun, Jang, Kiwon, Kim, Sang Cheol, Yang, Jin Ok, Park, Seongjin, Park, Kiejung, Choi, Jung Kyoon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499150/
https://ncbi.nlm.nih.gov/pubmed/26001967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv532
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