Splicing of a non-coding antisense transcript controls LEF1 gene expression

In this report we have analyzed the role of antisense transcription in the control of LEF1 transcription factor expression. A natural antisense transcript (NAT) is transcribed from a promoter present in the first intron of LEF1 gene and undergoes splicing in mesenchymal cells. Although this locus is...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Beltran, Manuel, Aparicio-Prat, Estel, Mazzolini, Rocco, Millanes-Romero, Alba, Massó, Pere, Jenner, Richard G., Díaz, Víctor M., Peiró, Sandra, de Herreros, Antonio García
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499130/
https://ncbi.nlm.nih.gov/pubmed/25990740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv502
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