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De novo design of heat-repressible RNA thermosensors in E. coli

RNA-based temperature sensing is common in bacteria that live in fluctuating environments. Most naturally-occurring RNA thermosensors are heat-inducible, have long sequences, and function by sequestering the ribosome binding site in a hairpin structure at lower temperatures. Here, we demonstrate the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hoynes-O'Connor, Allison, Hinman, Kristina, Kirchner, Lukas, Moon, Tae Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499127/
https://ncbi.nlm.nih.gov/pubmed/25979263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv499
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