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Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats
Aripiprazole is a wide-used antipsychotic drug with therapeutic effects on both positive and negative symptoms of schizophrenia, and reduced side-effects. Although aripiprazole was developed as a dopamine D(2) receptor (D(2)R) partial agonist, all other D(2)R partial agonists that aimed to mimic ari...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498891/ https://ncbi.nlm.nih.gov/pubmed/26162083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132722 |
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