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A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia

To investigate an oncogenic mutation of SETBP1 in the evolution from acute myelomonocytic leukemia (M4) to secondary aCML. Clinical data and molecular studies were analyzed of paired aCML and 'normal'DNA from a case with M4. We identified a mutation in SETBP1 (encoding a p.Asp868Ala altera...

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Detalhes bibliográficos
Publicado no:Clin Case Rep
Main Authors: Hu, WangQiang, Wang, XiaoXia, Yang, RongRong, Xie, YaoSheng, Zhang, Zhuo, Lu, Hong, Wu, LianFeng, Lai, MeiMei, Yu, Kang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498861/
https://ncbi.nlm.nih.gov/pubmed/26185647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.243
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