Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs

Canine distemper virus (CDV) vaccination confers long-term protection against CDV reinfection. To investigate the utility of CDV as a polyvalent vaccine vector for Leishmania, we generated recombinant CDVs, based on an avirulent Yanaka strain, that expressed Leishmania antigens: LACK, TSA, or LmSTI1...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Miura, Ryuichi, Kooriyama, Takanori, Yoneda, Misako, Takenaka, Akiko, Doki, Miho, Goto, Yasuyuki, Sanjoba, Chizu, Endo, Yasuyuki, Fujiyuki, Tomoko, Sugai, Akihiro, Tsukiyama-Kohara, Kyoko, Matsumoto, Yoshitsugu, Sato, Hiroki, Kai, Chieko
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498809/
https://ncbi.nlm.nih.gov/pubmed/26162094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003914
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