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Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels

The prognosis of hepatocellular carcinoma patients is usually poor, the size of tumors being a limiting factor for surgical treatments. Present results suggest that the overexpression of Gas1 (growth arrest specific 1) gene reduces the size, proliferating activity and malignancy of liver tumors. Mic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sacilotto, Natalia, Castillo, Josefa, Riffo-Campos, Ángela L., Flores, Juana M., Hibbitt, Olivia, Wade-Martins, Richard, López, Carlos, Rodrigo, M. Isabel, Franco, Luis, López-Rodas, Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498802/
https://ncbi.nlm.nih.gov/pubmed/26161998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132477
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