Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

OBJECTIVE: Several studies have reported that tacrolimus (TAC) significantly reduced proteinuria in lupus nephritis (LN) patients and mouse models. However, the mechanism for this effect remains undetermined. This study explored the mechanism of how TAC protects podocytes from injury to identify new...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liao, Ruyi, Liu, Qinghua, Zheng, Zhihua, Fan, Jinjin, Peng, Wenxing, Kong, Qingyu, He, Huijuan, Yang, Shicong, Chen, Wenfang, Tang, Xueqing, Yu, Xueqing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498640/
https://ncbi.nlm.nih.gov/pubmed/26161538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132724
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