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Two high-mobility group box domains act together to underwind and kink DNA

High-mobility group protein 1 (HMGB1) is an essential and ubiquitous DNA architectural factor that influences a myriad of cellular processes. HMGB1 contains two DNA-binding domains, box A and box B, which have little sequence specificity but have remarkable abilities to underwind and bend DNA. Altho...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Biol Crystallogr
Main Authors: Sánchez-Giraldo, R., Acosta-Reyes, F. J., Malarkey, C. S., Saperas, N., Churchill, M. E. A., Campos, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498601/
https://ncbi.nlm.nih.gov/pubmed/26143914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715007452
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