Evidence That Rhesus Macaques Self-Cure from a Schistosoma japonicum Infection by Disrupting Worm Esophageal Function: A New Route to an Effective Vaccine?

BACKGROUND: Rhesus macaques are unusual among schistosome hosts, self-curing from an established infection and thereafter manifesting solid immunity against a challenge, an ideal model for vaccine development. Previously, the immunological basis of self-cure was confirmed; surviving worms had ceased...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Li, Xiao-Hong, Xu, Yu-Xin, Vance, Gill, Wang, Yun, Lv, Long-Bao, van Dam, Govert J., Cao, Jian-Ping, Wilson, R. Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498593/
https://ncbi.nlm.nih.gov/pubmed/26161644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003925
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