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In Vivo Tibial Compression Decreases Osteolysis and Tumor Formation in a Human Metastatic Breast Cancer Model

Bone metastasis, the leading cause of breast cancer-related deaths, is characterized by bone degradation due to increased osteoclastic activity. In contrast, mechanical stimulation in healthy individuals upregulates osteoblastic activity, leading to new bone formation. However, the effect of mechani...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Lynch, Maureen E, Brooks, Daniel, Mohanan, Sunish, Lee, Min Joon, Polamraju, Praveen, Dent, Kelsey, Bonassar, Lawrence J, van der Meulen, Marjolein C H, Fischbach, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498485/
https://ncbi.nlm.nih.gov/pubmed/23649605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1966
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