Efficacy of Fewer than Three Doses of an HPV-16/18 AS04 adjuvanted Vaccine: Combined Analysis of Data from the Costa Rica Vaccine Trial and the PATRICIA Trial

BACKGROUND: Limited data suggest one or two doses of the HPV vaccines confer similar protection to the three-dose regimen. This study aimed to further evaluate the question of reduced-dose efficacy of the HPV-16/18 vaccine. METHODS: Summary-level data from the Costa Rica Vaccine Trial (CVT; NCT00128...

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Detalhes bibliográficos
Publicado no:Lancet Oncol
Main Authors: Kreimer, Aimée R, Struyf, Frank, Del Rosario-Raymundo, Maria Rowena, Hildesheim, Allan, Skinner, S Rachel, Wacholder, Sholom, Garland, Suzanne M, Herrero, Rolando, David, Marie-Pierre, Wheeler, Cosette M
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498478/
https://ncbi.nlm.nih.gov/pubmed/26071347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(15)00047-9
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