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The effects of short-term hypoxia on human mesenchymal stem cell proliferation, viability and p16(INK4A) mRNA expression: Investigation using a simple hypoxic culture system with a deoxidizing agent

A hypoxic environment is thought to be important for the maintenance of stemness and suppressing cell senescence, in stem cells. Therefore, a hypoxic condition is induced during cell expansion and/or induction of intended differentiation. However, the induction of these conditions requires a special...

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Pubblicato in:J Stem Cells Regen Med
Autori principali: Ito, Akira, Aoyama, Tomoki, Yoshizawa, Makoto, Nagai, Momoko, Tajino, Junichi, Yamaguchi, Shoki, Iijima, Hirotaka, Zhang, Xiangkai, Kuroki, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Journal of Stem Cells and Regenerative Medicine 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498321/
https://ncbi.nlm.nih.gov/pubmed/26195892
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