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Screening for UGT1A1 Genotype in Study A5257 Would Have Markedly Reduced Premature Discontinuation of Atazanavir for Hyperbilirubinemia

Background. Some patients are not prescribed atazanavir because of concern about possible jaundice. Atazanavir-associated hyperbilirubinemia correlates with UGT1A1 rs887829 genotype. We examined bilirubin-related discontinuation of atazanavir in participants from AIDS Clinical Trials Group Study A52...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Vardhanabhuti, Saran, Ribaudo, Heather J., Landovitz, Raphael J., Ofotokun, Ighovwerha, Lennox, Jeffrey L., Currier, Judith S., Olson, Lana M., Haas, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498287/
https://ncbi.nlm.nih.gov/pubmed/26180834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofv085
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