Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer

While viral antigens in HPV-related oropharyngeal cancer (HPVOPC) are attractive targets for immunotherapy, the effects of existing standard-of-care therapies on immune responses to HPV are poorly understood. We serially sampled blood from stage III–IV OPC patients undergoing concomitant chemoradiot...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Parikh, Falguni, Duluc, Dorothée, Imai, Naoko, Clark, Amelia, Misiukiewicz, Krzys, Bonomi, Marcello, Gupta, Vishal, Patsias, Alexis, Parides, Michael, Demicco, Elizabeth G., Zhang, David Y., Kim-Schulze, Seunghee, Kao, Johnny, Gnjatic, Sacha, Oh, Sangkon, Posner, Marshall, Sikora, Andrew G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498250/
https://ncbi.nlm.nih.gov/pubmed/25320012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1913
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