Deriving a cardiac ageing signature to reveal MMP-9-dependent inflammatory signalling in senescence

AIMS: Cardiac ageing involves the progressive development of cardiac fibrosis and diastolic dysfunction coordinated by MMP-9. Here, we report a cardiac ageing signature that encompasses macrophage pro-inflammatory signalling in the left ventricle (LV) and distinguishes biological from chronological...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Ma, Yonggang, Chiao, Ying Ann, Clark, Ryan, Flynn, Elizabeth R., Yabluchanskiy, Andriy, Ghasemi, Omid, Zouein, Fouad, Lindsey, Merry L., Jin, Yu-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498140/
https://ncbi.nlm.nih.gov/pubmed/25883218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv128
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