Tumor Necrosis Factor (TNF) Receptor Superfamily Member 1b on CD8(+) T Cells and TNF Receptor Superfamily Member 1a on Non-CD8(+) T Cells Contribute Significantly to Upper Genital Tract Pathology Following Chlamydial Infection

Background. We demonstrated previously that tumor necrosis factor α (TNF-α)–producing Chlamydia-specific CD8(+) T cells cause oviduct pathological sequelae. Methods. In the current study, we used wild-type C57BL/6J (WT) mice with a deficiency in genes encoding TNF receptor superfamily member 1a (TNF...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Manam, Srikanth, Thomas, Joshua D., Li, Weidang, Maladore, Allison, Schripsema, Justin H., Ramsey, Kyle H., Murthy, Ashlesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498131/
https://ncbi.nlm.nih.gov/pubmed/25552370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu839
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