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Matrix Metalloproteinase-9 Polymorphism 1562 C > T (rs3918242) Associated with Protection against Placental Malaria

Phagocytosis of malaria pigment (hemozoin) induces increased activity of matrix metalloproteinase (MMP)-9, an endopeptidase involved in cytokine regulation. In this study, we examined whether a common functional MMP-9 promoter polymorphism (rs3918242) affects Plasmodium falciparum infection in pregn...

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Bibliografiska uppgifter
I publikationen:Am J Trop Med Hyg
Huvudupphovsmän: Apoorv, Thittayil Suresh, Babu, Phanithi Prakash, Meese, Stefanie, Gai, Prabhanjan P., Bedu-Addo, George, Mockenhaupt, Frank P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Tropical Medicine and Hygiene 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497894/
https://ncbi.nlm.nih.gov/pubmed/26013370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.14-0816
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