Tight glycemic control with insulin does not affect skeletal muscle degradation during the early post-operative period following pediatric cardiac surgery

OBJECTIVE: Critical illness is associated with significant catabolism and persistent protein loss correlates with increased morbidity and mortality. Insulin is a potent anti-catabolic hormone; high-dose insulin decreases skeletal muscle protein breakdown in critically ill pediatric surgical patients...

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Pubblicato in:Pediatr Crit Care Med
Autori principali: Fisher, Jeremy G., Sparks, Eric A., Khan, Faraz A., Alexander, Jamin L., Asaro, Lisa A., Wypij, David, Gaies, Michael, Modi, Biren P., Duggan, Christopher, Agus, Michael S.D., Yu, Yong-Ming, Jaksic, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497866/
https://ncbi.nlm.nih.gov/pubmed/25850865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0000000000000413
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