A new α-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III

Rnt1 endoribonuclease, the yeast homolog of RNAse III, plays an important role in the maturation of a diverse set of RNAs. The enzymatic activity requires a conserved catalytic domain, while RNA binding requires the double-stranded RNA-binding domain (dsRBD) at the C-terminus of the protein. While b...

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Bibliographische Detailangaben
Hauptverfasser: Leulliot, Nicolas, Quevillon-Cheruel, Sophie, Graille, Marc, van Tilbeurgh, Herman, Leeper, Thomas C, Godin, Katherine S, Edwards, Thomas E, Sigurdsson, Snorri TL, Rozenkrants, Natasha, Nagel, Roland J, Ares, Manuel, Varani, Gabriele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC449770/
https://ncbi.nlm.nih.gov/pubmed/15192703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600260
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