Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo

Histamine is a mediator of allergic inflammation released mainly from mast cells. Although histamine strongly increases vascular permeability, its precise mechanism under in vivo situation remains unknown. We here attempted to reveal how histamine induces vascular hyperpermeability focusing on the k...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ashina, Kohei, Tsubosaka, Yoshiki, Nakamura, Tatsuro, Omori, Keisuke, Kobayashi, Koji, Hori, Masatoshi, Ozaki, Hiroshi, Murata, Takahisa
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497677/
https://ncbi.nlm.nih.gov/pubmed/26158531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132367
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