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Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors
Extracellular ATP is known to permeabilize certain cell types to polyatomic cations like YO-PRO1. Here, we report that extracellularly applied ATP stimulated rapid uptake and accumulation of an otherwise weakly membrane permeable fluorescent DNA-binding cytotoxin, Hoechst 33258, into cervical cancer...
Guardat en:
Publicat a: | FEBS Lett |
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Autors principals: | , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497545/ https://ncbi.nlm.nih.gov/pubmed/25937122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.04.044 |
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