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Transgenic rescue of insulin receptor–deficient mice
The role of different tissues in insulin action and their contribution to the pathogenesis of diabetes remain unclear. To examine this question, we have used genetic reconstitution experiments in mice. Genetic ablation of insulin receptors causes early postnatal death from diabetic ketoacidosis. We...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC449751/ https://ncbi.nlm.nih.gov/pubmed/15254588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421645 |
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