Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle

Duchenne muscular dystrophy (DMD) is a common X-linked disease characterized by widespread muscle damage that invariably leads to paralysis and death. There is currently no therapy for this disease. Here we report that a subpopulation of circulating cells expressing AC133, a well-characterized marke...

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Udgivet i:J Clin Invest
Main Authors: Torrente, Yvan, Belicchi, Marzia, Sampaolesi, Maurilio, Pisati, Federica, Meregalli, Mirella, D’Antona, Giuseppe, Tonlorenzi, Rossana, Porretti, Laura, Gavina, Manuela, Mamchaoui, Kamel, Pellegrino, Maria Antonietta, Furling, Denis, Mouly, Vincent, Butler-Browne, Gillian S., Bottinelli, Roberto, Cossu, Giulio, Bresolin, Nereo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI20325
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