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A randomized cross-over comparison of short-term exposure of once-daily extended release tacrolimus and twice-daily tacrolimus on renal function in healthy volunteers
Calcineurin inhibitor nephrotoxicity remains an issue for transplant recipients. The pharmacokinetic profile (PK) of the once-daily tacrolimus extended release (Tac-ER) includes equivalent exposure [AUC((0–24 h))] but lower C(max) versus twice-daily tacrolimus immediate release (Tac-IR). We hypothes...
Tallennettuna:
| Julkaisussa: | Transpl Int |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley & Sons, Ltd
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497360/ https://ncbi.nlm.nih.gov/pubmed/25160518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tri.12435 |
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