PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim

INTRODUCTION: Protein tyrosine kinase 6 (PTK6) is a non-receptor tyrosine kinase that is highly expressed in Human Epidermal Growth Factor 2(+) (Her2(+)) breast cancers. Overexpression of PTK6 enhances anchorage-independent survival, proliferation, and migration of breast cancer cells. We hypothesiz...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Breast Cancer Res
मुख्य लेखकों: Park, Sun Hee, Ito, Koichi, Olcott, William, Katsyv, Igor, Halstead-Nussloch, Gwyneth, Irie, Hanna Y.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496943/
https://ncbi.nlm.nih.gov/pubmed/26084280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0594-z
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