Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.

Transgenic mice were generated by using the alpha-myosin heavy chain promoter coupled to the coding sequence of a constitutively active mutant alpha 1B-adrenergic receptor (AR). These transgenic animals demonstrated cardiac-specific expression of this alpha 1-AR with resultant activation of phosphol...

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Detalles Bibliográficos
Main Authors: Milano, C A, Dolber, P C, Rockman, H A, Bond, R A, Venable, M E, Allen, L F, Lefkowitz, R J
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC44967/
https://ncbi.nlm.nih.gov/pubmed/7937846
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