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The Interplay between Alpha-Synuclein Clearance and Spreading

Parkinson’s Disease (PD) is a complex neurodegenerative disorder classically characterized by movement impairment. Pathologically, the most striking features of PD are the loss of dopaminergic neurons and the presence of intraneuronal protein inclusions primarily composed of alpha-synuclein (α-syn)...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Lopes da Fonseca, Tomás, Villar-Piqué, Anna, Outeiro, Tiago Fleming
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496680/
https://ncbi.nlm.nih.gov/pubmed/25874605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5020435
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