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Transcriptome Reprogramming by Plasmid-Encoded Transcriptional Regulators Is Required for Host Niche Adaption of a Macrophage Pathogen

Rhodococcus equi is a facultative intracellular pathogen of macrophages, relying on the presence of a conjugative virulence plasmid harboring a 21-kb pathogenicity island (PAI) for growth in host macrophages. The PAI encodes a family of 6 virulence-associated proteins (Vaps) in addition to 20 other...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Coulson, Garry B., Miranda-CasoLuengo, Aleksandra A., Miranda-CasoLuengo, Raúl, Wang, Xiaoguang, Oliver, Jenna, Willingham-Lane, Jennifer M., Meijer, Wim G., Hondalus, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496601/
https://ncbi.nlm.nih.gov/pubmed/26015480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00230-15
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