Hypothalamic POMC neurons promote cannabinoid-induced feeding

Hypothalamic pro-opiomelanocortin (POMC) neurons promote satiety. Cannabinoid receptor 1 (CB(1)R) is critical for central regulation of food intake. We interrogated whether CB(1)R-controlled feeding is paralleled by decreased activity of POMC neurons. Chemical promotion of CB(1)R activity increased...

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Publicat a:Nature
Autors principals: Koch, Marco, Varela, Luis, Kim, Jae Geun, Kim, Jung Dae, Hernandez, Francisco, Simonds, Stephanie E, Castorena, Carlos M, Vianna, Claudia R, Elmquist, Joel K, Morozov, Yury M, Rakic, Pasko, Bechmann, Ingo, Cowley, Michael A, Szigeti-Buck, Klara, Dietrich, Marcelo O, Gao, Xiao-Bing, Diano, Sabrina, Horvath, Tamas L
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496586/
https://ncbi.nlm.nih.gov/pubmed/25707796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14260
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