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Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells

Gouty arthritis is an inflammatory disease that is caused by an accumulation of monosodium urate (MSU) crystals in the joints. MSU is capable of activating the nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 (NLRP3) inflammasome, leading to interleukin-1β (IL-1β) se...

詳細記述

保存先:
書誌詳細
出版年:Cell Mol Immunol
主要な著者: Jhang, Jhih-Jia, Cheng, Yu-Ting, Ho, Cheng-Ying, Yen, Gow-Chin
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496538/
https://ncbi.nlm.nih.gov/pubmed/25109682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.65
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