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The mobility of single-file water molecules is governed by the number of H-bonds they may form with channel-lining residues

Channel geometry governs the unitary osmotic water channel permeability, p(f), according to classical hydrodynamics. Yet, p(f) varies by several orders of magnitude for membrane channels with a constriction zone that is one water molecule in width and four to eight molecules in length. We show that...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Horner, Andreas, Zocher, Florian, Preiner, Johannes, Ollinger, Nicole, Siligan, Christine, Akimov, Sergey A., Pohl, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496530/
https://ncbi.nlm.nih.gov/pubmed/26167541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1400083
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