Rapatar, a nanoformulation of rapamycin, decreases chemically-induced benign prostate hyperplasia in rats

Benign prostatic hyperplasia (BPH) is the most common age-related disease in men. Here we tested the efficacy of Rapatar, a micellar nanoformulation of rapamycin, in two rat models of BPH: testosterone-induced and sulpiride-induced hyperplasia in ventral lobes and lateral/dorsal lobes, respectively....

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發表在:Oncotarget
Main Authors: Lesovaya, Ekaterina A., Kirsanov, Kirill I., Antoshina, Elena E., Trukhanova, Lubov S., Gorkova, Tatiana G., Shipaeva, Elena V., Salimov, Ramiz M., Belitsky, Gennady A., Blagosklonny, Mikhail V., Yakubovskaya, Marianna G., Chernova, Olga B.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
主題:
Gerotarget (Focus on Aging): Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496392/
https://ncbi.nlm.nih.gov/pubmed/25991667
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