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Association of Beclin 1 expression with response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal carcinoma
Beclin 1 is an essential regulator of autophagy that is induced in response to cellular stress and serves to maintain cell survival in established tumors. We recently demonstrated that Beclin 1 suppression can sensitize colorectal cancer cells to radiation-induced DNA damage and apoptosis. Therefore...
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| Publicado no: | Int J Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4496267/ https://ncbi.nlm.nih.gov/pubmed/25708267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29496 |
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