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Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis

Claudin-2 enhances breast cancer liver metastasis and promotes the development of colorectal cancers. The objective of our current study is to define the regulatory mechanisms controlling Claudin-2 expression in breast cancer cells. We evaluated the effect of several Src Family Kinase (SFK) inhibito...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tabariès, Sébastien, Annis, Matthew G., Hsu, Brian E., Tam, Christine E., Savage, Paul, Park, Morag, Siegel, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496232/
https://ncbi.nlm.nih.gov/pubmed/25823815
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