Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis

Aberrant activation of Hedgehog (Hh) signaling is causative of BCCs and has been associated with a fraction of SCCs. Desmoglein 2 (Dsg2) is an adhesion protein that is upregulated in many cancers and overexpression of Dsg2 in the epidermis renders mice more susceptible to squamous-derived neoplasia....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Brennan-Crispi, Donna M., Hossain, Claudia, Sahu, Joya, Brady, Mary, Riobo, Natalia A., Mahoney, Mỹ G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496169/
https://ncbi.nlm.nih.gov/pubmed/25871385
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky