Apoptosis-related mitochondrial dysfunction defines human monocyte-derived dendritic cells with impaired immuno-stimulatory capacities

The death of dendritic cells (DCs) can potentially influence immune responses by affecting the duration of DC stimulation of lymphocytes. Here, we report that cultured mature monocyte-derived DCs manifest early mitochondrial damage (i.e. within 24 hrs), characterized by mitochondrial membrane potent...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Castera, Laurent, Hatzfeld-Charbonnier, Anne Sophie, Ballot, Caroline, Charbonnel, Florence, Dhuiege, Edith, Velu, Thierry, Formstecher, Pierre, Mortier, Laurent, Marchetti, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496146/
https://ncbi.nlm.nih.gov/pubmed/18466357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00358.x
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