Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy

PURPOSE: Radiofrequency thermal ablation (RFA) of hepatic and renal tumors can be accompanied by non-desired tumorigenesis in residual, untreated tumor. Here, we studied the use of micelle-encapsulated siRNA to suppress IL-6-mediated local and systemic secondary effects of RFA. METHODS: We compared...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ahmed, Muneeb, Kumar, Gaurav, Navarro, Gemma, Wang, Yuanguo, Gourevitch, Svetlana, Moussa, Marwan H., Rozenblum, Nir, Levchenko, Tatyana, Galun, Eithan, Torchilin, Vladimir P., Goldberg, S. Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495977/
https://ncbi.nlm.nih.gov/pubmed/26154425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128910
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