IGF-1 decreases portal vein endotoxin via regulating intestinal tight junctions and plays a role in attenuating portal hypertension of cirrhotic rats

BACKGROUND: Intestinal barrier dysfunction is not only the consequence of liver cirrhosis, but also an active participant in the development of liver cirrhosis. Previous studies showed that external administration of insulin-like growth factor 1 (IGF-1) improved intestinal barrier function in liver...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Zhao, Tian-Yu, Su, Li-Ping, Ma, Chun-Ye, Zhai, Xiao-Han, Duan, Zhi-Jun, Zhu, Ying, Zhao, Gang, Li, Chun-Yan, Wang, Li-Xia, Yang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495682/
https://ncbi.nlm.nih.gov/pubmed/26152281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0311-5
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