Sensitization of Chemo-Resistant Human Chronic Myeloid Leukemia Stem-Like Cells to Hsp90 Inhibitor by SIRT1 Inhibition

Development of effective therapeutic strategies to eliminate cancer stem-like cells (CSCs), which play a major role in drug resistance and disease recurrence, is critical to improve cancer treatment outcomes. The current investigation was undertaken to examine the effectiveness of the combination tr...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Kim, Hak-Bong, Lee, Su-Hoon, Um, Jee-Hyun, Kim, Mi-Ju, Hyun, Suh-Kyung, Gong, Eun-Ji, Oh, Won Keun, Kang, Chi-Dug, Kim, Sun-Hee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495410/
https://ncbi.nlm.nih.gov/pubmed/26157347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10896
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