Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus

With severe injury or disease, microglia become chronically activated and damage the local brain environment, likely contributing to cognitive decline. We previously discovered that microglia are dependent on colony-stimulating factor 1 receptor (CSF1R) signaling for survival in the healthy adult br...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Rice, Rachel A., Spangenberg, Elizabeth E., Yamate-Morgan, Hana, Lee, Rafael J., Arora, Rajan P. S., Hernandez, Michael X., Tenner, Andrea J., West, Brian L., Green, Kim N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495246/
https://ncbi.nlm.nih.gov/pubmed/26156998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0336-15.2015
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