Cell-Autonomous Regulation of Mu-Opioid Receptor Recycling by Substance P

How neurons coordinate and reprogram multiple neurotransmitter signals is an area of broad interest. Here, we show that substance P (SP), a neuropep-tide associated with inflammatory pain, reprograms opioid receptor recycling and signaling. SP, through activation of the neurokinin 1 (NK1R) receptor,...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Bowman, Shanna L., Soohoo, Amanda L., Shiwarski, Daniel J., Schulz, Stefan, Pradhan, Amynah A., Puthenveedu, Manojkumar A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494997/
https://ncbi.nlm.nih.gov/pubmed/25801029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.045
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